Research Priorities

The AAE has defined the knowledge areas in which the specialty should focus the greatest attention. These priorities change in response to developments in clinical practice.

  1. Assessment of Clinical Outcomes

    1. Factors affecting success of endodontic treatment
      1. Nonsurgical and surgical endodontic treatment
      2. Effect of number of visits
      3. Effect of instrumentation and obturation techniques
      4. Timeliness and quality of the coronal restoration
      5. Effect of the dental operating microscope on the success of nonsurgical retreatment and surgical endodontic treatment
      6. Effect of residual microorganisms following instrumentation and/or medication
    2. Management of anxiety, infection, inflammation and pain
      Long-term cost-effectiveness of endodontic treatment compared to treatment alternatives
  2. Assessment of New Technology Such as Devices and Materials

  3. Biology of Pulpal and Periradicular Tissues

    1. Focal infection (relationship, if any, of endodontic treatment to systemic diseases)
      1. Fate of remaining microorganisms in endodontically treated teeth and the supporting periodontium
      2. Effects of acute and chronic periradicular infections and their management on systemic health
      3. Epidemiological relationship between endodontic treatment and systemic diseases
      4. Pathogenesis and healing of endodontic infections in patients with chronic systemic diseases
    2. Development of sophisticated methods of diagnosis including enhanced imaging of teeth and periradicular tissues
    3. Identification, clarification, and use of neurotransmitters, growth factors, genetic or genomic factors, and other biologic regulators to manage endodontic disease
    4. Effect of endodontic materials on local tissue response and systemic health
    5. Contribution of microorganisms to the pathogenesis of pulpal and periradicular disease
  4. Cracks and Fractures in Teeth

    1. Diagnosis of cracked teeth
    2. Management of cracked teeth and repair of root fractures
    3. Investigation of treatment modalities for vital teeth and endodontically treated teeth
    4. Development of in vitro and in vivo model systems to evaluate materials, techniques, and assessment of clinical outcomes
    5. Epidemiology of cracked teeth and endodontic sequelae
  5. Demographics/Epidemiology of Pulpal and Periradicular Disease

    1. Current and projected demand for endodontic services
    2. Prevalence of pulpal and periradicular disease and projections
    3. Current and projected status of the endodontic practice
  6. Endodontic/Implant Relationships

    1. Relationship between endodontically treated teeth and adjacent implant(s)
    2. Assessment of clinical outcomes of implants vs. endodontically treated teeth
  7. External and Internal Resorption

    1. Etiology and biology of root resorption
    2. Effective treatment modalities with assessment of clinical outcomes
  8. Educational Research

    1. Current and projected status of endodontic education
    2. Development and assessment of creative models and application of these models in graduate student, dental student, and continuing education programs
    3. Design of innovative programs that would use technology to improve the quality and efficiency of graduate student, dental student, and continuing education programs
    4. Development of a telecommunication system, “teledentistry,” to enhance continuing education and consultations
  9. Tissue Engineering—Regeneration of the Pulpodentin Complex and Periradicular Tissues

    1. Optimal scaffold materials and signaling molecules needed to regenerate the pulp-dentin complex and periradicular tissues
    2. Source of cells needed to regenerate pulp-dentin complex and periradicular tissues
    3. Molecular processes that control stem cell activity within the pulp-dentin complex
    4. The fate of the stem cells within the pulp-dentin and periradicular tissues
    5. Advantages and disadvantages of different sources of cells to regenerate the pulp-dentin complex and periradicular tissues
    6. Animal models that can be used to replicate disease conditions and test hypotheses related to regenerating the pulp-dentin complex and periradicular tissues
    7. The influence of enhanced methods of disinfecting and shaping the root and root canal system on regenerative procedures
    8. Identification of desirable/undesirable outcomes of regenerative procedures
    9. Identification of appropriate outcome measures of regenerative endodontic procedures for example; in vivo imagining, laser Doppler flowmetry, micro-CT, etc.
    10. Patient and clinical factors affecting the outcomes of regenerative endodontic procedures