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Guidelines for Medication-Related Osteonecrosis Jaw: An Update

The medical use of bisphosphate drugs, both I.V. and oral, along with other antiresorptive and antiangiogenic drugs for the treatment of cancer and osteoporosis, has increased rapidly over the past 20-plus years. There is increasing awareness of these drugs’ possible adverse side effect of Bisphosphate-associated Osteonecrosis of the Jaw (BONJ). This is a severe adverse drug reaction, consisting of progressive bone destruction in the maxillofacial region of the patient.

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New Antibiotic Guidelines: Is There Anything Truly Novel?

In the November issue of JADA, an Evidence-based Clinical Practice Guideline was published to assist clinicians and patients in determining the appropriate use of systemic antibiotics for the urgent management of endodontic emergencies.

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Treating the Medically Compromised Patient

We know that dental anxiety alone can result in increased blood pressure, syncope, irritability and diaphoresis. However, underlying medical conditions such as hypertension, diabetes and thyroid abnormalities, etc., may also be associated with the same manifestations.

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AAE Issues New Guidelines on the Use of Systemic Antibiotics in Endodontics

Read about the AAE’s new guidelines regarding the use of antibiotics in conjunction with endodontic treatment.

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Ibuprofen: How Well Do You Know Your Favorite Drug?

With its tried and proven efficacy, it is easy to see why ibuprofen is one of the analgesics of choice by endodontists.

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Analgesics: Balancing the Equation

“Take two aspirin and call me in the morning.” This decades-old statement was what many patients were “prescribed” by their doctor when complaining of a minor malady.

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Antibiotics: A Risky Prescription

The adverse effects of overusing and misusing antibiotics are highly publicized in the health professional literature, most recently in the August issue of the Journal of the American Dental Association. According to the Centers for Disease Control and Prevention, more than 2 million people in the United States are hospitalized and more than 23,000 die each year from superinfections caused by antibiotic-resistant bacteria. Clostridium difficile is a particularly vicious resistant bacterium. A major two-year review of antimicrobial resistance reached the grim conclusion that, without drastic curbs, drug-resistant superbugs could claim millions of lives worldwide each year. These superbugs have the potential to become a greater killer than cancer by 2050. Yet, despite the potential dangers and limited usefulness of antibiotics in dentistry and endodontics, their use is common and possibly increasing.

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